Endogenous / BiologyEndogenousHuman-supportedUpdated 2026-04-24

Peptide reference file

Secretin

Trending #40 in Endogenous2.1k searches/moProven

Secretin is an endogenous gut peptide that coordinates pancreatic bicarbonate secretion and digestive signaling.

Current readout: human-supported evidence, endogenous status, endogenous approval state, human evidence appears in the current trail, registered trials are linked, and 3 linked sources in the seed trail.

PubChem CID 16129665 | 9136 PubMed results | 52 trial records | 3 DailyMed labels | 4 Drugs@FDA applications

Secretin is mostly discussed because it belongs in the index because gut-peptide biology is bigger than GLP-1 alone.

The public claim is straightforward: It belongs in the index because gut-peptide biology is bigger than GLP-1 alone. Strong digestive peptide biology with real clinical relevance.

In plain language, secretin is an endogenous gut peptide that coordinates pancreatic bicarbonate secretion and digestive signaling.

Human-supportedEndogenous
Gut hormonePancreatic secretionDigestive signaling

Aliases: Secretin hormone

SpecimenSecretin specimen
CCCCHHHHHHHNO
Formula
C130H219N43O42
Mass
3056.4
Evidence
Human-supported
Elements
4

Most commonly discussed in relation to Gut hormone, Pancreatic secretion, Digestive signaling.

What Secretin is

Secretin is an endogenous gut peptide that coordinates pancreatic bicarbonate secretion and digestive signaling.

Secretin is grouped under Endogenous / Biology / Approved / Clinical on PeptideFactCheck because it belongs in the index because gut-peptide biology is bigger than GLP-1 alone.

The useful starting point is to separate the molecule itself from the internet story around it. It belongs in the index because gut-peptide biology is bigger than GLP-1 alone.

Why people keep looking it up

It belongs in the index because gut-peptide biology is bigger than GLP-1 alone.

Secretin is an endogenous gut peptide that coordinates pancreatic bicarbonate secretion and digestive signaling.

Secretin tends to stay in the conversation because it touches a familiar public theme: gut hormone, pancreatic secretion, and digestive signaling. That makes it easy for the claim to travel faster than the evidence.

What the evidence can support right now

Strong digestive peptide biology with real clinical relevance.

Human physiology is well established, and diagnostic use also exists.

Mechanistic support is strong across digestive physiology.

Why this page carries the current tier: Strong digestive peptide biology with real clinical relevance.

The current seed trail for Secretin is pulling from 2 databases sources and 1 literature source.

Safety, limits, and regulatory context

This is a physiology-reference entry more than a consumer peptide topic.

Secretin is tracked here primarily as endogenous and diagnostic biology.

Editorial boundary: PeptideFactCheck does not publish dosing, cycling, sourcing, injection, or administration instructions for Secretin. The job here is to explain the public claim, the mechanism story, the evidence strength, and the current limits.

Molecular and identifier data

The current PubChem match for Secretin is CID 16129665. That gives the page a source-backed chemistry record rather than a placeholder identifier block.

PubChem CID
16129665
Formula
C130H219N43O42
Molecular weight
3056.4
InChIKey
KKNIUBFRGPFELP-UHFFFAOYSA-N

Matched synonyms include Vitrum, Secretina, Secretine, Secretinum, SECRETIN-FERRING, 1393-25-5, 88C55N56UU, SecretinKABI.

Open PubChem record

Clinical trial snapshot

The current ClinicalTrials.gov intervention query for Secretin returns 52 study records. This does not prove efficacy by itself, but it does show whether the peptide is showing up in a formal trial registry rather than only in forums or vendor copy.

Literature snapshot

The current PubMed query for Secretin returns 9136 results. The articles below are a quick literature surface so the page shows actual papers instead of only generic evidence labels.

Label and regulatory records

For approved or clinically developed peptides, the page now pulls in official labeling and FDA-facing records where they exist. That makes the regulatory section materially more useful than a generic approved or not-approved tag.

Brand names
Digestive Enzyme Drops 2018
Generic names
DIGESTIVE ENZYME DROPS
Routes
ORAL
Application numbers
Not linked

Indications and usage. INDICATIONS For the temporary relief of indigestion, heartburn, or abdominal discomfort or bloating.*

Source trail

Each linked source is shown directly so the page can be audited. The page now combines its editorial seed trail with automated official-source enrichment generated on 2026-04-24 from PubChem, ClinicalTrials.gov, PubMed, DailyMed, openFDA label, and Drugs@FDA.

Safety noteThis content is educational only and does not replace medical advice. Peptide use may carry risks and should be discussed with a qualified medical professional.