Fitness + RecoveryClinical / investigationalEarly humanUpdated 2026-04-22

Peptide reference file

CJC-1295

Trending #3 in Fitness24.8k searches/moMixed

CJC-1295 is a growth hormone releasing hormone analog designed to stimulate the GH/IGF-1 axis for longer than native GHRH.

Current readout: early human evidence, clinical / investigational status, investigational approval state, human evidence appears in the current trail, registered trials are linked, and 4 linked sources in the seed trail.

PubChem CID 91971820 | 29 PubMed results | 1 trial record | 0 DailyMed labels | 0 Drugs@FDA applications

CJC-1295 is mostly discussed because it appears frequently in body-composition, recovery, and longevity discussions, especially paired with secretagogues.

The public claim is straightforward: People look at CJC-1295 for growth-hormone signaling, body composition, recovery, sleep, and anti-aging claims. Human endocrine effects exist, but broad physique, recovery, and longevity claims go beyond what is proven.

In plain language, cJC-1295 mimics growth hormone releasing hormone, telling the body to release more growth hormone signal in studied settings.

Early humanClinical / investigational
GHRH analogGH axisIGF-1

Aliases: DAC-GRF, Modified GRF 1-29 with DAC

SpecimenCJC-1295 specimen
CCCCHHHHHHHNO
Formula
C165H269N47O46
Mass
3647.2
Evidence
Early human
Elements
4

Most commonly discussed in relation to GHRH analog, GH axis, IGF-1.

What CJC-1295 is

CJC-1295 is a growth hormone releasing hormone analog designed to stimulate the GH/IGF-1 axis for longer than native GHRH.

CJC-1295 is grouped under Fitness + Recovery / Longevity + Skin on PeptideFactCheck because it appears frequently in body-composition, recovery, and longevity discussions, especially paired with secretagogues.

The useful starting point is to separate the molecule itself from the internet story around it. It is framed as a way to push the GH/IGF-1 axis rather than taking growth hormone directly.

Why people keep looking it up

People look at CJC-1295 for growth-hormone signaling, body composition, recovery, sleep, and anti-aging claims.

CJC-1295 mimics growth hormone releasing hormone, telling the body to release more growth hormone signal in studied settings.

CJC-1295 tends to stay in the conversation because it touches a familiar public theme: ghrh analog, gh axis, and igf-1. That makes it easy for the claim to travel faster than the evidence.

What the evidence can support right now

Human endocrine effects exist, but broad physique, recovery, and longevity claims go beyond what is proven.

Early human studies have evaluated endocrine effects, but that is narrower than most performance claims online.

Mechanistic rationale comes from GHRH signaling and peptide modification for extended exposure.

Why this page carries the current tier: Human endocrine signal exists, but broad optimization claims remain much less settled.

The current seed trail for CJC-1295 is pulling from 1 literature source, 1 trials source, 1 databases source, and 1 safety source.

Safety, limits, and regulatory context

Potential unknowns include endocrine spillover, glucose effects, edema-like effects, and long-term risk from manipulating the GH axis.

No FDA-approved CJC-1295 drug product is listed in this V1 source trail.

Editorial boundary: PeptideFactCheck does not publish dosing, cycling, sourcing, injection, or administration instructions for CJC-1295. The job here is to explain the public claim, the mechanism story, the evidence strength, and the current limits.

Molecular and identifier data

The current PubChem match for CJC-1295 is CID 91971820. That gives the page a source-backed chemistry record rather than a placeholder identifier block.

PubChem CID
91971820
Formula
C165H269N47O46
Molecular weight
3647.2
InChIKey
ZUQGTWKGESAQCD-ZGFIGYLBSA-N

Matched synonyms include CJC 1295, 62RC32V9N7, DTXSID501027567, CJC1295, RefChem:918751, DTXCID701513160, GRF 1-29 (CJC1295), 446262-90-4.

Open PubChem record

Clinical trial snapshot

The current ClinicalTrials.gov intervention query for CJC-1295 returns 1 study records. This does not prove efficacy by itself, but it does show whether the peptide is showing up in a formal trial registry rather than only in forums or vendor copy.

Literature snapshot

The current PubMed query for CJC-1295 returns 29 results. The articles below are a quick literature surface so the page shows actual papers instead of only generic evidence labels.

Source trail

Each linked source is shown directly so the page can be audited. The page now combines its editorial seed trail with automated official-source enrichment generated on 2026-04-24 from PubChem, ClinicalTrials.gov, PubMed, DailyMed, openFDA label, and Drugs@FDA.

Safety noteThis content is educational only and does not replace medical advice. Peptide use may carry risks and should be discussed with a qualified medical professional.